[Antitumor action and other regulatory effects of low intensity electromagnetic and chemical factors in experiment].

This paper presents a brief overview of the results of the original researches of biological responses induced by agents of cytostatic and regulatory actions in small doses, as well as weak electromagnetic radiation of different frequency bands. The possibility of obtaining the expressed antitumor, antistress and geroprotective effects has been shown. The question of the relation of system mechanisms of realization of these effects with structural rearrangements in biological fluids, as well as the promising directions for optimizing the therapeutic properties of the informational impacts are discussed.

Signs of cell-cell interactions in sarcoma 45 tissue under conditions of antitumor effect caused by injection of magnetite nanoparticles.

Changes in transplanted sarcoma 45 tissue in outbred albino rats with tumor regression under the effect of magnetite nanoparticles (magnetic fluid) were studied by light and electron microscopy. The ultrastructure and cell death types in regressing tumors and signs of cell-cell interactions with participation of macrophages, lymphocytes, neutrophils, and degranulating mast cells were described. Some possible mechanisms of a pronounced antitumor activity of magnetite nanoparticles were discussed.

[High-frequency oscillations in a pulse wave signal and their relation to differential blood count leucocytes].

High-frequency oscillations in a pulse wave signal in the range of 1-50 Hz and their relation to differential blood count leucocytes have been investigated. It is shown that the correlation coefficients grow in the frequency range of 1-12.5 Hz between high-frequency oscillations in a pulse wave signal and stab neutrophils, monocytes and segmented granulocytes.

Morphofuctional aspects of antitumor activity of low-intensity microwave resonance radiation in experiment.

Effects of low-intensity microwave radiation with bioactive frequency were studied in rats with transplanted sarcoma 45. After exposure to microwave radiation in the regimen of activation therapy, the antitumor effect was observed in 50% animals (marked inhibition of tumor growth or its partial regression). Light and electron microscopy revealed destructive changes in the tumor tissue, accumulation of activation of immune system cells, and signs of the increase in tumor cell differentiation.