Publications by authors named "L Kauppila"

Multiple system atrophy (MSA) is a sporadic and progressive neurodegenerative disorder with a complex differential diagnosis. A range of disorders- also of nondegenerative etiology- can mimic MSA, expanding its differential diagnosis. Both misdiagnosis and diagnostic delays are relatively common in clinical practice.

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Article Synopsis
  • * Intravenous thrombolysis (IV-rtPA) for acute ischemic stroke (AIS) may lead to myocardial infarction (MI), with studies indicating a higher incidence of cardiac events among those treated with thrombolysis. * A review of AIS patients revealed that only 0.5% experienced MI within 24 hours post-IV-rtPA, with 54% of cases attributed to atherosclerosis and 46% to embolism; significant associations were found between the type of MI and characteristics of the stroke. * While MI after IV-rtPA is rare, the rate of embolic MI was higher than in the general population, suggesting a possible link between the underlying causes of AIS and MI, though the small
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Background: Gait impairments are among the most common and impactful symptoms of Parkinson's disease (PD). Recent technological advances aim to quantify these impairments using low-cost wearable systems for use in either supervised clinical consultations or long-term unsupervised monitoring of gait in ecological environments. However, very few of these wearable systems have been validated comparatively to a criterion of established validity.

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Mobile health (mHealth) has emerged as a potential solution to providing valuable ecological information about the severity and burden of Parkinson's disease (PD) symptoms in real-life conditions. : The objective of our study was to explore the feasibility and usability of an mHealth system for continuous and objective real-life measures of patients' health and functional mobility, in unsupervised settings. : Patients with a clinical diagnosis of PD, who were able to walk unassisted, and had an Android smartphone were included.

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