Publications by authors named "L Kamp"
ZNRF3, a negative regulator of β-catenin signaling, removes Wnt receptors from the membrane. Currently, it is unknown which tumor-associated variants can be considered driver mutations and through which mechanisms they contribute to cancer. Here we show that all truncating mutations analyzed at endogenous levels exhibit loss-of-function, with longer variants retaining partial activity.
View Article and Find Full Text PDFEfficacy of 30% silver diamine fluoride compared to atraumatic restorative treatment in arresting dentin caries lesions in preschoolers: a randomized clinical trial.
Clin Oral Investig
December 2024
Objective: To compare the efficacy of silver diamine fluoride (SDF) and atraumatic restorative treatment (ART) in arresting caries lesions. Variables such as treatment time, adverse effects/parental aesthetic perception, anxiety and patients' behavior were also evaluated.
Materials And Methods: Children (3.
Objectives: Arterial calcification is thought to protect against rupture of intracranial aneurysms, but studies in a representative population of intracranial aneurysm patients have not yet been performed. The aim was to compare the prevalence of aneurysm wall calcification and intracranial carotid artery calcification (ICAC) between patients with an unruptured intracranial aneurysm (UIA) and a ruptured intracranial aneurysm (RIA).
Materials And Methods: We matched 150 consecutive UIA patients to 150 RIA patients on age and sex.
Objectives: Patients with an unruptured intracranial aneurysm (UIA) may experience scanxiety around follow-up imaging. We studied the prevalence and temporal pattern of scanxiety, and compared quality of life (QoL) outcomes in patients with and without scanxiety.
Methods: We performed a prospective cohort study in a tertiary referral center in the Netherlands between October 2021 and November 2022.
Article Synopsis
- In patients with an unruptured brain bulge (called an aneurysm), using a special dye (gadolinium) to check the wall can tell us if it might grow or burst.
- Researchers studied many patients to see if the dye could predict these issues, taking into account the size of the aneurysm.
- They found that while the dye shows some connection with growth or rupture, it doesn’t really help if you already know the size of the aneurysm, so doctors might not need to use it for short-term predictions.