Deep brain stimulation - A primer for psychiatrists.

Deep Brain Stimulation is a form of neurostimulation where electrical stimulation is delivered via intracranial electrodes over specific subcortical targets. It has been increasingly used as an alternative to ablative procedures for psychiatric disorders refractory to standard treatments. This review describes the common psychiatric indications for DBS, the current evidence base, putative mechanisms, and future directions.

Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury.

Disorders in pulmonary vascular integrity are a prominent feature in many lung diseases. Paracrine signaling is highly enriched in the lung and plays a crucial role in regulating vascular homeostasis. However, the specific local cell-cell crosstalk signals that maintain pulmonary microvascular stability in adult animals and humans remain largely unexplored.

Surface Engineered Nanoparticles Coupled with Pattern Recognition Techniques for Rapid Identification and Discrimination of Multiple Thiols in a Real Sample Matrix.

Thiols, including Cysteine (CYS) and Glutathione (GSH), play pivotal roles in numerous physiological processes as they are integral components of many essential biomolecules and are found abundantly in foods such as additives and antioxidants. Any deviations in thiol concentrations can disrupt normal physiological functions, affecting the body's metabolism and potentially leading to diseases such as Alzheimer's and Parkinson's diseases, etc. Consequently, the imperative need for developing reliable and robust techniques for thiol analysis is crucial for early disease detection and ensuring food safety.

Telemedicine in Pediatric Diabetes Care: The Way Forward?

Objective: Data regarding the efficacy and feasibility of telemedicine services in type 1 diabetes (T1D) are sparse in India. This study was planned to assess non-inferiority of glycemic control and diabetes knowledge score after outreach care via telemedicine.

Methods: The study enrolled persons with T1D (age £ 25 years).

Genotypic diversity and virulence factors of Klebsiella pneumoniae in a North Indian tertiary care hospital.

Klebsiella pneumoniae, a pathogen of concern worldwide can be classified as classical K. pneumoniae (cKp) and Hypervirulent K. pneumoniae (HvKp).