Liver transplantation (LTX) using donors after controlled circulatory death (cDCD) is associated with poorer graft survival and increased incidence of nonanastomotic biliary strictures (NASs) compared to livers procured from brain-dead donors (DBD). The use of normothermic regional perfusion (NRP) during cDCD procurement may improve posttransplant outcomes and reduce the incidence of NAS. In Sweden, cDCD LTX was introduced through a national pilot protocol with mandatory NRP.
View Article and Find Full Text PDFBackground: Extracorporeal membrane oxygenation (ECMO) is indicated for patients with severe respiratory and/or circulatory failure. The standard technique to visualize the extent of pulmonary damage during ECMO is computed tomography (CT).
Purpose: This single-center, retrospective study investigated whether pulmonary blood flow (PBF) measured with echocardiography can assist in assessing the extent of pulmonary damage and whether echocardiography and CT findings are associated with patient outcomes.
During the COVID-19 pandemic, governments worldwide implemented nonpharmaceutical lockdown policies to mitigate the impact of the virus. The effectiveness of these policies depended on public support, and they came with serious consequences for the population. Given that people's perceptions can influence their support for lockdown policies, we aimed to elicit perceptions of policy stringency among people in Denmark, France, Germany, Italy, the Netherlands, Portugal, and the United Kingdom in early 2021 as part of the European Covid Survey.
View Article and Find Full Text PDFExpert Rev Clin Immunol
February 2024
Introduction: Patients with chronic graft versus host disease (cGVHD) have low circulating regulatory T cells (Tregs). Interleukin-2(IL-2) is a growth factor for Tregs, and clinical trials have explored its use in cGVHD patients.
Areas Covered: Here we will discuss the biology of IL-2, its rationale for use and results of clinical trials in cGVHD.