Publications by authors named "L K Joe"
Transmission of immune responses from one generation to the next represents a powerful adaptive mechanism to protect an organism's descendants. Parental infection by the natural C. elegans pathogen Pseudomonas vranovensis induces a protective response in progeny, but the bacterial cues and intergenerational signal driving this response were previously unknown.
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- The study explores access to donor human milk (DHM) in California neonatal intensive care units (NICUs) and highlights structural barriers that contribute to inequities.
- DHM access is more common in NICUs serving predominantly white families, while those with greater proportions of Hispanic families and uninsured patients face significant barriers to access.
- Addressing these structural issues through policy changes could improve DHM availability for marginalized communities, reducing health disparities among NICU infants.
Article Synopsis
- - Women with gestational diabetes mellitus (GDM) are less likely to intend to exclusively breastfeed compared to those without diabetes, and they report higher odds of using formula both in the hospital and at home.
- - Many participants, regardless of GDM status, shared a common belief that breastfeeding may lower the risk of developing type 2 diabetes mellitus (T2DM), indicating a lack of awareness about the benefits of breastfeeding in this context.
- - Among women with GDM, "medical reasons" were frequently cited as a justification for formula supplementation, highlighting a potential gap in education regarding breastfeeding practices and their benefits related to T2DM risk.
The ability of mitochondria to coordinate stress responses across tissues is critical for health. In C. elegans, neurons experiencing mitochondrial stress elicit an inter-tissue signaling pathway through the release of mitokine signals, such as serotonin or the Wnt ligand EGL-20, which activate the mitochondrial unfolded protein response (UPR) in the periphery to promote organismal health and lifespan.
View Article and Find Full Text PDFCellular homeostasis is intricately influenced by stimuli from the microenvironment, including signaling molecules, metabolites, and pathogens. Functioning as a signaling hub within the cell, mitochondria integrate information from various intracellular compartments to regulate cellular signaling and metabolism. Multiple studies have shown that mitochondria may respond to various extracellular signaling events.
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