Publications by authors named "L Juillard"
Article Synopsis
- The study aimed to create and evaluate a deep learning algorithm for automatically segmenting kidneys and renal cysts in patients with autosomal dominant polycystic kidney disease (ADPKD) using MRI scans.
- Researchers used a combination of historical MRI data and added normal renal scans to train the algorithm, comparing its results to those from human raters to measure accuracy.
- While the algorithm performed fairly well within the variability of human ratings, it tended to underestimate the total kidney and cyst volume, particularly in cases with very large cyst volumes.
Article Synopsis
- A study called FABRYDIAL aimed to determine how common Fabry disease (FD) is among dialysis patients aged 18 to 74 in France, involving 124 dialysis centers and excluding cases of nephropathy unrelated to FD.
- Out of 6,032 targeted patients, 3,088 (73.6%) were included, with biochemical and genetic tests conducted on samples to identify potential cases of FD.
- The findings revealed a low prevalence of FD: 0.058% in males, 0% in females, and 0.035% overall, suggesting that while rare, signs of FD should be investigated in patients with unexplained kidney issues due to its serious implications if diagnosed early.
Article Synopsis
- Over the last few decades, strategies have been developed to improve the removal of retained molecules in patients with kidney failure, helping them tolerate fluid removal better and live longer.
- The effectiveness of these treatments depends on how individual patient factors interact with the characteristics of the devices used and the treatment plans prescribed.
- This article reviews various blood purification techniques, highlighting their unique features and how they aim to enhance patient care in nephrology.
Background: Creatinine-based equations such as the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) are recommended for estimating glomerular filtration rate (eGFR) in clinical practice, but have reduced performance in advanced stages of chronic kidney disease. However, only rarely studies have evaluated the performance of eGFR by measuring the average of the urinary clearances of creatinine and urea (mCl) compared with the eGFR equations.
Methods: This cross-sectional study evaluated the usefulness of mCl in a population of 855 participants who performed a GFR measurement by urinary inulin clearance.
Background And Objectives: Activation of the complement system is involved in the pathogenesis of anti-glomerular basement membrane (anti-GBM) disease. Glomerular deposits of complement 3 (C3) are often detected on kidney biopsies. The primary objective of this study was to analyze the prognostic value of the serum C3 level and the presence of C3 glomerular deposits in patients with anti-GBM disease.
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