Sensitivity of noncommercial computer-aided detection system for mammographic breast cancer detection: pilot clinical trial.

Purpose: To evaluate a noncommercial computer-aided detection (CAD) program for breast cancer detection with screening mammography.

Materials And Methods: A CAD program was developed for mammographic breast cancer detection. The program was applied to 2,389 patients' screening mammograms at two geographically remote academic institutions (institutions A and B).

Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts.

Fibroadenomas are the most common benign tumors of the female breast and are associated with a slight increase in the risk of subsequent breast cancer. Multiple fibroadenomas have been described in patients after renal transplantation and are thought to be secondary to drug-related growth stimulation. Epstein-Barr virus (EBV) has been detected in many neoplasms, including breast cancer.

Digital mammography: observer performance study of the effects of pixel size on the characterization of malignant and benign microcalcifications.

Rationale And Objectives: The authors performed this study to evaluate the effects of pixel size on the characterization of mammographic microcalcifications by radiologists.

Materials And Methods: Two-view mammograms of 112 microcalcification clusters were digitized with a laser scanner at a pixel size of 35 microm. Images with pixel sizes of 70, 105, and 140 microm were derived from the 35-microm-pixel size images by averaging neighboring pixels.

Mammographic appearance of breast cancer in African-American women: report of 100 consecutive cases.

Rationale And Objectives: The authors determined the mammographic appearance of breast carcinoma in African-American women and compared it with that in a white cohort.

Materials And Methods: The authors reviewed the mammograms, clinical records, and pathology records of 97 consecutive African-American women with 100 confirmed breast cancers and 110 white women with 111 confirmed breast cancers.

Results: The mammograms obtained in African-American women were positive in 94 cases (94%), and those obtained in white women were positive in 99 cases (89%).

Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.

Purpose: To determine the mammographic features of locally advanced breast carcinoma treated with neoadjuvant chemotherapy and to evaluate the accuracy of mammography in the prediction of residual carcinoma.

Materials And Methods: Of 90 women treated with hormonally synchronized cytotoxic therapy before mastectomy or lumpectomy for advanced breast carcinoma, 56 were selected because they had undergone mammography before and after neo-adjuvant therapy. Mammographic and clinical opinion on the presence of residual disease was compared with histologic results.