Publications by authors named "L Joyeux"
Background: General anesthesia during pregnancy is not uncommon, for example, for trauma surgery, cerclage, or cesarean delivery. Current recommendations are to maintain maternal partial pressure of carbon dioxide in arterial blood (paCO2) at 30 mm Hg, which is based solely on the average maternal paCO2 in awake pregnant women. However, there is no evidence that this target, compared to other targets, would enable optimal conditions for the fetus during general anesthesia.
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- * A total of 200 MMC cases were analyzed, showing that fetoscopic surgeries had longer median gestational ages at delivery and a significant percentage of vaginal births without major complications like uterine rupture.
- * At the 30-month mark, children who underwent fetal interventions were more likely to be able to walk independently, and fewer required surgeries for complications such as tethered cord syndrome or spinal cysts compared to those who had postnatal repairs.
The aim of this pragmatic approach to retrospective observational study was to identify the end-tidal concentration of sevoflurane which was associated with optimal surgical conditions (i.e., absence of any movement, coughing and straining) in 127 pregnant sheep.
View Article and Find Full Text PDFWe systematically reviewed experiments in the fetal lamb model of gastroschisis using PubMed, Embase, Web of Science, and Scopus, seeking for standardized surgical techniques to obtain complex gastroschisis. Eligible were studies where an abdominal wall defect was surgically induced and gross anatomical findings at birth were available. The primary outcome was complex gastroschisis, defined by the presence of bowel stenosis, atresia, volvulus, perforation, and/or necrosis.
View Article and Find Full Text PDFObjective: To evaluate medium-term self-reported respiratory and gastrointestinal (GI) outcomes in children with congenital diaphragmatic hernia (CDH).
Design: Self-reported respiratory and GI outcomes correlated with prenatal severity indicators.
Setting: Prospective study at three fetal medicine units.