A Spectroscopy Solution for Contactless Conductivity Detection in Capillary Electrophoresis.

This paper introduces a novel contactless single-chip detector that utilizes impedance-to-digital conversion technology to measure impedance in the microfluidic channel or capillary format analytical device. The detector is designed to operate similarly to capacitively coupled contactless conductivity detectors for capillary electrophoresis or chromatography but with the added capability of performing frequency sweeps up to 200 kHz. At each recorded data point, impedance and phase-shift data can be extracted, which can be used to generate impedance versus frequency plots, or phase-shift versus frequency plots.

Advancing 3D Spheroid Research through 3D Scaffolds Made by Two-Photon Polymerization.

Three-dimensional cancer cell cultures have been a valuable research model for developing new drug targets in the preclinical stage. However, there are still limitations to these in vitro models. Scaffold-based systems offer a promising approach to overcoming these challenges in cancer research.

Erratum: Direct Mechanical Detection and Measurement of Wave-Matter Orbital Angular Momentum Transfer by Nondissipative Vortex Mode Conversion [Phys. Rev. Lett. 123, 244301 (2019)].

This corrects the article DOI: 10.1103/PhysRevLett.123.

Peculiarities of Integrating Mechanical Valves in Microfluidic Channels Using Direct Laser Writing.

Regenerative medicine is a fast expanding scientific topic. One of the main areas of development directions in this field is the usage of additive manufacturing to fabricate functional components that would be later integrated directly into the human body. One such structure could be a microfluidic valve which could replace its biological counterpart in veins as it is worn out over the lifetime of a patient.

Fabrication of Microfluidic Tesla Valve Employing Femtosecond Bursts.

Expansion of the microfluidics field dictates the necessity to constantly improve technologies used to produce such systems. One of the approaches which are used more and more is femtosecond (fs) direct laser writing (DLW). The subtractive model of DLW allows for directly producing microfluidic channels via ablation in an extremely simple and cost-effective manner.