Background: According to the emotion regulation process, situation selection comprises actions that increase or decrease the likelihood of being in contexts that foster a certain type of emotion, positive or negative. This concept is complemented by the social basis theory, which starts with the assumption that the primary ecology of humans is characterized by its social components. Thus, reduced access to social relationships increases cognitive and physiological effort, which leads to a decrease in well-being.
View Article and Find Full Text PDFIntroduction: Leprosy reactions (LRs) are inflammatory responses observed in 30%-50% of people with leprosy. First-line treatment is glucocorticoids (GCs), often administered at high doses with prolonged courses, resulting in high morbi-mortality. Methotrexate (MTX) is an immunomodulating agent used to treat inflammatory diseases and has an excellent safety profile and worldwide availability.
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