A Comparative Study of Two Topical Treatments for Photoaging of the Hands.

Background: Multiple effective treatments exist for correction of skin photoaging. Topical L-ascorbic acid (vitamin C), a well-known antioxidant and topical human platelet extract (HPE), is a novel off-the-shelf cosmetic ingredient that has shown positive results in recent clinical studies. HPE is a leukocyte-depleted allogeneic product derived from United States-sourced, pooled, apheresed platelets produced with consistent batch quality, purity, and effect.

Safety and efficacy of human platelet extract in skin recovery after fractional CO laser resurfacing of the face: A randomized, controlled, evaluator-blinded pilot study.

Background: Fractional carbon dioxide (CO ) laser resurfacing is used successfully for facial rejuvenation. Post procedure skincare is a variable that influences downtime caused by pain/tenderness, erythema, crusting, and bruising.

Aims: The primary objective of this pilot study was to demonstrate the benefits of human platelet extract (HPE) (plated)™ CALM Serum, a new topical cosmetic product, following fractionated CO ablative laser resurfacing treatment to the entire face versus standard of care.