Ten-year follow-up on the performance of a telemetric intracranial pressure sensor.

A permanently implanted epidural sensor has permitted long term telemetric intracranial pressure monitoring in selected neurosurgical patients. The sensor, consisting only of an inductance and a pressure-sensitive capacitance, has been implanted in 127 patients. Of these 127 patients, 13 have continued to have the sensor in place for 4 to 9 years (average, 6.

Sclerosteosis: neurogenetic and pathophysiologic analysis of an American kinship.

We studied an American kinship with sclerosteosis, an autosomal-recessive disorder of bone remodeling and bone overgrowth of the calvaria, skull base, and tubular bones. Unlike osteopetrosis, which is attributed to abnormal immune and osteoclast function as well as bone resorption, sclerosteosis appears to be primarily a disorder of osteoblast (bone formation) hyperactivity. Related to cranial vascular and neural foraminal narrowing and reduced intracranial volume, affected patients with sclerosteosis demonstrate frequent seventh nerve palsy, progressive optic and cranial neuropathies, mixed hearing loss, brainstem compression, intracranial hypertension with increased elastance, and sudden, premature death.

Continuous intracranial pressure recording in adult hydrocephalus.

An implantable intracranial pressure sensor was used to diagnose and monitor the treatment of 17 adults with hydrocephalus. The intracranial pressure sensor was implanted before shunting in most cases and patients were studied in a sleep laboratory for two nights during which the intracranial pressure was measured throughout the night. Cases included five examples of acute hydrocephalus secondary to tumor, subarachnoid hemorrhage or meningitis, and 12 cases of long standing hydrocephalus diagnosed as normal pressure hydrocephalus, aque-ductal stenosis, or hydrocephalus ex vacuo.