Publications by authors named "L J Simar"

Due to increasing consumption and urbanisation, urban waste management and recycling are a primary concern in Italy. Italian waste collection underwent significant reform with the introduction of a sorted collection target of 65% of total collected waste in Legislative Decree No. 152/2006.

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Waste management is crucial for advancing the circular economy, and Italy has begun to address this issue by organizing municipalities into collaborative communities of municipalities, named ATOs. In this paper, we propose a quantitative approach based on conditional efficiency analysis to estimate viable eco-efficiency targets for these waste collection communities. The proposed targets are both eco-efficient, because they reflect optimal resource allocation within the eco-efficiency framework, and viable, because they consider the unique specificities of each waste community.

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When hospital financing depends on a budget which in turn depends on the pathologies being treated, it is necessary to detect hospital stays which show discrepancies between the resources they consume and the medical characteristics they present. Deterministic nonparametric frontier models are used to rank hospital stays according to their expenses taking into account the severity of the patients' conditions. As these models are very sensitive to the extreme stays, a robust frontier model, the order-m frontier is used.

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Human follicular dendritic cell (FDC)-like cells (FLC) have been utilized for the in vitro analysis of germinal center reactions. However, there is no consensus whether FLC represent FDC in vitro. The purpose of the present study has therefore been to determine distinguishing features of FDC and FLC in vitro.

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Lymph follicles are globular and compact due to aggregation of lymphoid cells on follicular dendritic cells (FDC). To probe the mechanisms underlying this accumulation of cells, we analyse here the role played by FDCs in attracting and binding cells. FDCs prepared from human tonsils by mild separation techniques appeared in the form of clusters (FDC clusters), where, via cytoplasmic extensions, they enveloped lymphoid cells.

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