Publications by authors named "L J Romeo"

Objective: To determine whether the bioactive sphingolipid sphingosine 1-phosphate (S1P) modulates cellular proliferation and synthesis of fibrotic proteins in leiomyoma differently than myometrial cells.

Design: A basic science study using human leiomyoma and myometrial cells.

Patient(s): Not applicable.

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Article Synopsis
  • This study focuses on creating a new fixed bed bioreactor designed for scalable adherent cell culture, which is vital for advancing cell and gene therapies.
  • The bioreactor features stacked mesh discs for efficient fluid flow and minimal stress on cells, showing excellent uniformity in media distribution during cell growth.
  • The platform is highly effective for automated cell harvesting and maintains a high cell viability rate while allowing for predictable modeling of cell growth, making it a promising tool for large-scale biomanufacturing.
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The U.S. Gulf of Mexico contains a complex network of existing, decommissioned, and abandoned oil and gas pipelines, which are susceptible to a number of stressors in the natural-engineered offshore system including corrosion, environmental hazards, and human error.

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Introduction: Many minimally invasive techniques have been developed over the years to treat primary ventral hernias and rectus abdominis diastasis, all of which have their advantages and disadvantages in terms of complications, reproducibility, and cost. We present a case-series of a novel approach that was safe and reproducible in a cohort of 17 patients.

Patients And Methods: All patients in the study underwent the novel procedure between October 2022 and July 2023.

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Article Synopsis
  • The use of AI in Clinical Decision Support Systems (CDSS) can really change healthcare and help doctors make better decisions, especially in emergencies.
  • However, creating these AI systems comes with challenges, like making sure they are fair and don’t have biases.
  • To make sure AI is used ethically and effectively, hospitals need to set up special departments that focus on combining human judgment with smart algorithms.
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