Changes in Erythrocytes in 88 Hyperthyroid Cats.

Background: There is only a limited number of studies that show alterations in erythrocytes in feline hyperthyroidism. Discrepancies between the findings of these studies may be caused by the presence of concurrent diseases and the use of various haematological analysers.

Methods: This study analysed changes in red blood cells (RBCs) in 88 hyperthyroid cats without concurrent diseases, to identify associations between observed changes and to assess the influence of serum thyroxine (T4) concentration, cat age, and sex, on RBC changes.

Canine Babesiosis Caused by Large Species: Global Prevalence and Risk Factors-A Review.

Canine babesiosis is a disease caused by protozoan pathogens belonging to the genus . Four species of large cause canine babesiosis (, , , and the informally named ). Although canine babesiosis has a worldwide distribution, different species occur in specific regions: in sub-Saharan Africa, in Europe and Asia, and in the Eastern Atlantic United States, while occurs in Africa, southern parts of Europe and Asia, northern Australia, southern regions of North America, and in South America.

Pathogenesis of Anemia in Canine Babesiosis: Possible Contribution of Pro-Inflammatory Cytokines and Chemokines-A Review.

Canine babesiosis is a tick-borne protozoan disease caused by intraerythrocytic parasites of the genus . The infection may lead to anemia in infected dogs. However, anemia is not directly caused by the pathogen.

Fatty Acid Binding Protein 1 Modulates Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic Homeostasis in Obese Mice.

Background: The parasitic trematode evades host immune defenses through secretion of various immunomodulatory molecules. Fatty Acid Binding Proteins (FABPs) are among the main excreted/secreted proteins and have been shown to display anti-inflammatory properties. However, little is currently known regarding their impact on dendritic cells (DCs) and their subsequent capacity to prime specific CD4 T cell subsets.

The Role of Nuclear Factor Kappa B (NF-κB) in the Immune Response against Parasites.

The immune system consists of various cells, organs, and processes that interact in a sophisticated manner to defend against pathogens. Upon initial exposure to an invader, nonspecific mechanisms are raised through the activation of macrophages, monocytes, basophils, mast cells, eosinophils, innate lymphoid cells, or natural killer cells. During the course of an infection, more specific responses develop (adaptive immune responses) whose hallmarks include the expansion of B and T cells that specifically recognize foreign antigens.