Publications by authors named "L J Niccolai"

Monitoring physiological indicators including heart rate (HR) is crucial for managing animal welfare across diverse settings, from precision livestock farming to wildlife conservation. HR is a reliable indicator of energy expenditure and stress, yet the invasive nature of HR loggers limits their application in wild and free-ranging species. This study explores whether overall dynamic body acceleration (ODBA), measured with an external accelerometer, can serve as a less invasive proxy for HR.

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  • - The study aimed to identify barriers that prevent people from consistently using four common tickborne disease (TBD) prevention measures, including tick checks, insect repellent application, showering after outdoor activities, and pesticide use in yards.
  • - An online survey with 1883 respondents from high Lyme disease areas in Connecticut and Maryland revealed that forgetting and concerns about safety or convenience were the most common reasons for not following these prevention measures.
  • - Key findings showed that many people were unaware of specific measures, found them too troublesome, or were concerned about the safety of chemicals for themselves, pets, and the environment, highlighting the need for better public health messaging.
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  • Nirsevimab, a monoclonal antibody, has shown promise in preventing RSV-related lower respiratory tract infections (LRTIs) in clinical trials, but further real-world evaluation is necessary.* -
  • This study analyzed data from Yale New Haven Health System to assess nirsevimab's effectiveness in preventing RSV infections among infants, focusing on factors like disease severity, dosage, and time since vaccination.* -
  • Among 3,090 infants, nirsevimab demonstrated a 68.4% effectiveness overall, with higher effectiveness rates of 80.5% for hospitalizations and 84.6% for severe cases, highlighting its potential in real-world settings.*
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Although invasive cervical cancer (ICC) rates have declined since the advent of screening, the annual age-adjusted ICC rate in the United States remains 7.5 per 100,000 women. Failure of recommended screening and management often precedes ICC diagnoses.

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In 2019, the CDC expanded their recommendations for human papillomavirus (HPV) vaccination beyond age 26 years to include shared clinical decision-making (SCDM) among adults aged 27-45 years ("mid-adults"). The purpose of this study was to describe HPV vaccination status among mid-adult women before the implementation of SCDM for HPV vaccination. A cross-sectional survey was conducted during 2016-2019 in Connecticut, United States, and enrolled women born in 1981 or later (birth cohorts eligible for HPV vaccination).

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