Publications by authors named "L J Jara-Quezada"

Article Synopsis
  • The update of the Mexican Guidelines for the Treatment of Systemic Lupus Erythematosus has been developed with input from various experts across the country.
  • The new guidelines follow the GRADE system, which helps in evaluating the quality of evidence for healthcare recommendations.
  • Key new topics included in the update are vaccines, pregnancy, and cardiovascular risk, which were not addressed in the previous guidelines from 2017.
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Antiphospholipid antibody syndrome (usually named antiphospholipid syndrome, APS) is an autoimmune disorder seen mainly in young people. Clinically, APS is described by pregnancy complications and/or a hypercoagulable state, including the venous or arterial vasculature, and strongly related to antiphospholipid antibodies. Although several cardiac manifestations have been involved with APS, and accelerated atherosclerosis is present in this condition, little is known about cardiovascular (CV) risk and the relation between APS.

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Background: COVID-19 brought with it unknowns related to systemic sclerosis.

Objective: To know the clinical evolution and prognosis of COVID-19 in a cohort of patients with systemic sclerosis.

Methods: During the pandemic, we had digital contact with a cohort of 197 patients with SSc.

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Article Synopsis
  • The study investigates whether blood groups (BG) influence susceptibility to SARS-CoV-2 infection among healthcare workers prior to vaccination.
  • Using a cross-sectional design, researchers compared the blood groups, antibody presence, and symptoms of 102 convalescent health workers against 116 controls from March to June 2020.
  • Results indicated that blood group O was the most common among both groups, with a non-significant lower risk of infection associated with BG-O and a potential higher risk for BG-A, while 15% of the convalescent group did not develop antibodies post-infection.
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Rheumatoid arthritis (RA) is an autoimmune inflammatory disease with an increased prevalence in Mexico. Although its etiology is unknown, its development can be influenced by environmental factors such as smoking and viral infections. But among the factors influencing susceptibility, it is the genetic factors that predominate, mainly the HLA-DRB1 genes, and specifically the alleles that have the shared epitope (SE).

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