Publications by authors named "L J Huerta"

Background: Bone transport in distraction osteogenesis is an effective, well-known procedure. However, bone compression is an aspect of this technique for which there is no objective information. The lack of direct bone compression measurements may result in a lack of uniformity in the bone transport process, which can result in its ineffective application and may be contributing to its underutilization.

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Background: Transgender women are a key population in the HIV epidemic globally, including in Peru. This cross-sectional epidemiological study characterized the pre-exposure prophylaxis (PrEP) cascade in adolescent and young adult transgender women in Peru to inform roll-out of early HIV prevention efforts.

Methods: Between February-July 2022, a community-recruited sample of HIV-negative or status unknown young transgender women ( = 140) in Peru completed a socio-behavioral survey and biological testing for HIV and bacterial STIs.

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Article Synopsis
  • - The study aimed to explore how TFE3 rearrangement affects recurrence in renal cell carcinoma (RCC) and emphasized the importance of immunohistochemistry (IHC) in the diagnostic process.
  • - Among 695 RCC patients, 22 showed signs of TFE3 rearrangement, with FISH testing confirming 8 had TFE3-rearranged-RCC, which was associated with a significantly higher recurrence rate compared to clear cell RCC (50% vs 18.8%).
  • - The findings indicate that TFE3 rearrangement is a key independent prognostic factor for recurrence and shorter progression-free survival, highlighting the need for further studies and careful patient follow-up.
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  • The study investigates how integrating point of care (POC) echocardiography in managing septic shock affects patient outcomes in the ICU following the Surviving Sepsis Campaign guidelines.
  • A total of 1701 articles were reviewed, and after filtering, seven studies with 3885 patients were included, showing that POC echocardiography is linked to lower in-hospital and 28-day mortality rates, more frequent use of inotropic support, and faster lactate clearance.
  • The researchers concluded that while POC echocardiography can improve some outcomes in septic shock management, more extensive studies are needed to confirm these findings and explore additional treatment effects.
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