Longitudinal performance trajectories of young female sprint runners: a new tool to predict performance progression.

Background: Longitudinal performance tracking in sports science is crucial for accurate talent identification and prognostic prediction of future performance. However, traditional methods often struggle with the complexities of unbalanced datasets and inconsistent repeated measures.

Purpose: This study aimed to analyze the longitudinal performance development of female 60 m sprint runners using linear mixed effects models (LMM).

Axon demyelination and degeneration in a zebrafish model of hereditary spastic paraplegia.

Hereditary spastic paraplegias (HSPs) are a diverse set of neurological disorders characterized by progressive spasticity and weakness in the lower limbs caused by damage to the axons of the corticospinal tract. More than 88 genetic mutations have been associated with HSP, yet the mechanisms underlying these disorders are not well understood. We replicated the pathophysiology of one form of HSP known as spastic paraplegia 15 (SPG15) in zebrafish.

Tacrolimus Monitoring in Liver Transplant Recipients, Posttransplant Cholestasis: A Comparative Between 2 Commercial Immunoassays and a Liquid Chromatography-Tandem Mass Spectrometry Method.

Background: Cholestasis commonly occurs after orthotopic liver transplantation. It can be extrahepatic because of mechanical obstruction or intrahepatic because of various causes. During cholestasis episodes, blood concentrations of tacrolimus (TAC) metabolites may increase, potentially affecting TAC concentrations measured by immunoassays.

Why age categories in youth sport should be eliminated: Insights from performance development of youth female long jumpers.

Long-term sports participation and performance development are major issues in popular sports and talent development programs. This study aimed to provide longitudinal trends in youth female long jump performance development, participation, and relative age effects (RAEs), as longitudinal data for female athletes are missing. 51'894 season's best results of female long jump athletes ( = 16'189) were acquired from the Swiss Athletics online database and analyzed within a range of 6-22 years of age.

A Markerless Pose Estimator Applicable to Limbless Animals.

The analysis of kinematics, locomotion, and spatial tasks relies on the accurate detection of animal positions and pose. Pose and position can be assessed with video analysis programs, the "trackers." Most available trackers represent animals as single points in space (no pose information available) or use markers to build a skeletal representation of pose.