Publications by authors named "L J Djukanovic"
Article Synopsis
- * The exact cause of peripartum cardiomyopathy is unclear, although factors like age, lifestyle, and genetics may play a role; recent theories suggest that an abnormal form of prolactin may contribute to the heart damage.
- * Ongoing research explores treatments like bromocriptine, a drug that inhibits prolactin, and highlights the importance of safe medication use during pregnancy and breastfeeding, particularly to protect both mothers and their babies.
Although acute heart failure (AHF) is a common disease associated with significant symptoms, morbidity and mortality, the diagnosis, risk stratification and treatment of patients with hypertensive acute heart failure (H-AHF) still remain a challenge in modern medicine. Despite great progress in diagnostic and therapeutic modalities, this disease is still accompanied by a high rate of both in-hospital (from 3.8% to 11%) and one-year (from 20% to 36%) mortality.
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- The incidence of myocarditis is rising due to better diagnostic criteria and methods, despite challenges in accurately determining its frequency in the general population.
- The disease is complicated by various causes, changing clinical presentations, and the need for tailored diagnostic and treatment approaches, especially with the influence of immune-mediated processes and cancer treatments.
- Diagnosis typically starts with clinical signs and non-invasive methods like cardiac MRI, while treatment options include managing heart failure, immunotherapy, and, in severe cases, heart transplantation, with the goal of reducing the high mortality associated with this condition.
Background and Objectives: In the development of type 2 diabetes mellitus (T2DM) and its complications, genetic and environmental factors play important roles. Diabetic nephropathy (DN), one of the major microangiopathic chronic diabetic complications, is associated with an increased risk of major cardiovascular events and all-cause mortality. The present study was designed to investigate the possible modifying effect of glutathione transferase polymorphisms (GSTM1, GSTT1, GSTP1 rs1138272/rs1695, GSTO1 rs4925 and GSTO2 rs156697) in the susceptibility to T2DM and diabetic nephropathy.
View Article and Find Full Text PDFBackground/aim: Despite technological advances in diagnosis and treatment, in-hospital mortality with acute aortic dissection type B is still about 11%. The purpose of this study was to assess the risk factors for early and long-term adverse outcomes in patients with acute aortic dissection type B treated medically or with conventional open surgery.
Methods: The present study included 104 consecutive patients with acute aortic dissection type B treated in our Center from January 1, 1998 to January 1, 2007.