Curdlan inclusion modifies the rheological properties and the helix-coil transition behavior of gelatin and increases the flexibility of gelatin films.

Gelatin, a natural and edible polymer, has attracted wide attention for use in food and edible packaging applications. However, its inadequate properties, especially poor flexibility, limit its broader utilization. Hybridizing different polymers is a promising strategy to achieve enhanced properties.

Dual-mode strategy for the determination of vanillin in milk-based products based on molecular-imprinted nanozymes.

The inclusion of artificial food additives such as vanillin in infant formula should be strictly monitored to mitigate potential negative impacts on the dietary habits and health of infants. This raises a necessity of an accurate inspection and prompt feedback of vanillin in infant foods. In this study, colorimetric and fluorescent dual-mode assays based on CuNS/FeO@MIPs were established to detect vanillin selectively and sensitively.

In Vivo tissue healing mechanism at the intestinal anastomosis site following high-frequency electric welding.

To investigate the effect of High-Frequency Electric Welding (HFEW) on intestinal tissue healing, we performed end-to-end anastomosis experiments in New Zealand rabbits. Within one week post-surgery, animals exhibited normal vital signs, replaced necrotic tissue with healthy collagen, and showed improved tissue strength while inflammation decreased. By day 60, tissue pathology and function fully recovered, resembling normal tissue.

Sativene-Related Sesquiterpenoids with Phytotoxic and Plant-Promoting Activities from the Plant Pathogenic Fungus Based on a Molecular Networking Strategy.

Sativene-related sesquiterpenoids including -sativene analogs are a large member of fungal secondary metabolites with phytotoxic and growth-promoting effects on different plants. In this report, a series of sativene-related sesquiterpenoids with diverse carbon skeletons (-, sativene/isosativene/-sativene/cyclosativene/-isosativene ring systems) were isolated from the plant pathogenic fungus based on a molecular networking strategy. The undescribed structures were elucidated based on NMR spectra, X-ray diffraction analysis, chemical derivation, and calculated electronic circular dichroism calculations.

Paroxetine promotes longevity via ser-7-dop-4-IIS axis in Caenorhabditis elegans.

Paroxetine, a selective serotonin reuptake inhibitor, is widely used in the clinical treatment of depression. While several antidepressants show promise as geroprotectors, the role of paroxetine in aging remains unclear. In this study, we evaluated the lifespan extension effect of paroxetine in Caenorhabditis elegans (C.