B-Guide System: Improving the Predictability of Complete-Arch Implant and Prosthetic Placement Using Fixed Prosthesis Guides.

Objective: Computer-aided implant placement (CAIP) offers improved accuracy and reduced invasiveness. However, traditional static CAIP (sCAIP) protocols for complete-arch restorations often involve multiple guides and clinical steps, increasing the risk of soft tissue trauma and procedural complexity. This article introduces the B-guide technique, which integrates implant placement and interim prosthesis delivery into a single device to simplify the procedure and minimize tissue damage.

Effect of a and -based biofertilizer on phosphorus acquisition and grain yield of soybean.

Introduction: Phosphate-solubilizing bacteria that function through acidification (organic acid synthesis) or mineralization (production of enzymes such as phytase and phosphatases) have been explored as a biotechnological alternative to enhance plant access to phosphorus (P) retained in organic and inorganic forms in agricultural soils. This study tested the hypothesis that applying a biofertilizer composed of a recognized phosphate-solubilizing bacterium ( - endophytic strain BVPS01) and an underexplored plant growth-promoting bacterium ( - endophytic strain BVPS02) would improve the growth and grain yield of L. plants.

A specific phosphorylation-dependent conformational switch in SARS-CoV-2 nucleocapsid protein inhibits RNA binding.

The nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 encapsidates the viral genome and is essential for viral function. The central disordered domain comprises a serine-arginine-rich (SR) region that is hyperphosphorylated in infected cells. This modification regulates function, although mechanistic details remain unknown.

Synergic Effect of the Antimicrobial Peptide ToAP2 and Fluconazole on Biofilms.

is one of the agents of invasive candidiasis, a life-threatening disease strongly associated with hospitalization, particularly among patients in intensive care units with central venous catheters. This study aimed to evaluate the synergistic activity of the antifungal peptide ToAP2 combined with fluconazole against biofilms grown on various materials. We tested combinations of different concentrations of the peptide ToAP2 with fluconazole on biofilms.