Mentalization-based treatment for psychotic disorder: a rater-blinded, multi-center, randomized controlled trial.

Background: Impaired mentalizing ability - an impaired ability to understand one's own and other people's behavior in terms of mental states - is associated with social dysfunction in non-affective psychotic disorder (NAPD). We tested whether adding mentalization-based treatment for psychotic disorder (MBTp) to treatment as usual (TAU) results in greater improvement in social functioning.

Methods: Multicenter, rater-blinded, randomized controlled trial.

The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells.

Background: Butamben or n-butyl-p-aminobenzoate is a long-acting experimental local anesthetic for the treatment of chronic pain when given as an epidural suspension. We have investigated whether Cav1.2/L-type calcium channels may be a target of this butamben action.