Publications by authors named "L Iu Tikhomirova"

Article Synopsis
  • The study measured the electrical impedance and pulsation ranges of brachial and femoral arteries in rats after 14 days of hindlimb unloading (a model for microgravity).
  • Results showed that the femoral artery constricted while the brachial artery dilated, with both exhibiting reduced pulsation dynamics.
  • The ability of the femoral artery to switch to an active pulsatile mode during bloodletting was significantly lower in unloaded rats than in control rats, indicating potential negative effects of microgravity on blood circulation.
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The study examined the modes of pulsations of the femoral and carotid arteries of rats in situ (n=14) during acute blood loss, which sequentially caused a deep BP drop, cardiac and respiration arrest, and termination of ECG signals. When BP dropped to 19 (13; 26) mm Hg, the mechanosensitivity of passively pulsing arteries determined by the ratio of the swing range of electroimpedance oscillations of arterial segment to pulse pressure increased by 3.2 (2 ; 4) times (p<0.

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In experiments on narcotized male rats (n=85), the mean electroimpedance Z and peak-to-peak magnitudes (the swing ranges) of passive (ΔZ) and active (ΔZ) pulsatile electroimpedance oscillations of isolated segment of femoral arteries were determined in situ. These rheographic parameters (RP) were measured in intact animals and in those with modeled chronic myocardial infarction, chronic denervation of the right hind leg, as well as in rats subjected to sham operations to mimic denervation or infarction (with thoracic trauma). The rats with modeled myocardial infarction demonstrated decreasing trends of all RP.

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The inclusion of public health and health care measures in labor functions of professional standards of medical specialists increased significance of mastering of these standards by students during specialty training, since on this depends their successful completion of primary accreditation of specialists and implementation of job descriptions in the course of daily activities. The purpose of the study was to analyze factors determining qualitative of mastering the discipline "Public health and Health Care" by students of medical educational organizations. The analytical, logical, statistical, questionnaire survey and direct ranking methods were applied.

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