[NAD- and NADP-diaphorase activity in the peripheral blood lymphocytes of patients with the B-cell variant of chronic lympholeukemia].

The authors studied the cytotoxic function, activity of NAD- and NADP-diaphorases in the peripheral blood lymphocytes in 57 patients with B-cellular variant of chronic lympholeukoses and found a significant reduction of the natural killer activity of lymphocytes, increased activity of NADP-diaphorase. Reduction of natural killer activity in patients with B-cell variant of chronic lympholeukoses did not depend on the activity of membrane diaphorases in peripheral blood lymphocytes.

[The vitamin B1 and C content in the tissues of animals with thyrotoxicosis].

The authors studied the effect of toxic doses of thyroxin on the content of vitamins C and B1 in different tissues of rats. On the 15-th day after administration of thyroxin one could observe a reduction of thiamin in the tissues of the animals. These changes were most pronounced in the liver.

[Effect of three retinoids on the growth of experimental tumors].

Influence of retinoid C17-diester retinyldimedone and L-tocopherylretinoate on the growth of transplanted tumors was investigated in F1 (C57Bl/6 X CBA) strain of mice. The retinoids studied proved to be less toxic than retinoic acid. Both retinoid C17-diester and L-tocopherylretinoate reduced growth of cervical cancer, while retinyldimedone inhibited growth of Lewis carcinoma (lung tumor) and of stomach carcinoma.