Publications by authors named "L I Zhuangzhuang"
Article Synopsis
- The study aimed to compare the anti-inflammatory effects of three herbal decoctions (QF, HS, XF) against COVID-19 using experimental models with SARS-CoV-2 stimulators.
- RAW264.7 macrophages and a mouse endotoxemia model were utilized to assess the influence of these decoctions on various inflammatory cytokines.
- Results showed all three decoctions reduced pro-inflammatory markers, with QF showing the strongest effects, suggesting potential clinical applications for treating inflammation in severe COVID-19 cases.
Traditional Chinese Medicine (TCM) has been extensively used as a mainstay for treating various pathologies. Combing the pharmacology and systems biology approaches, the network pharmacology (NP) approach was developed to predict the probable mechanism underlying the therapeutic effect of TCM. However, approaches solely based on NP cannot effectively elucidate the curative mechanism in a holistic and reliable manner due to limitations in NP-based methods and complexity of TCM components.
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