Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward.

The global market demand for natural astaxanthin (AXT) is growing rapidly owing to its potential human health benefits and diverse industry applications, driven by its safety, unique structure, and special function. Currently, the alga Haematococcus pluvialis (alternative name H. lacustris) has been considered as one of the best large-scale producers of natural AXT.

Sibanin, a novel black fly-derived Kunitz protease inhibitor, prevents thrombus formation in mice by anticoagulation-antiplatelet duality.

Most Kunitz inhibitors exhibit serine protease inhibitory activity, but limited information is available on the regulation of platelet function. Herein, we report the purification and characterization of a novel single Kunitz domain inhibitor (Sibanin) from the salivary glands of the black fly Simulium bannaense. Recombinant Sibanin prolonged activated partial thromboplastin time and prothrombin time, and exhibited high-affinity binding to FXa and elastase with a KD of 5.

Searching to extrapolate embedding for out-of-graph node representation learning.

Out-of-graph node representation learning aims at learning about newly arrived nodes for a dynamic graph. It has wide applications ranging from community detection, recommendation system to malware detection. Although existing methods can be adapted for out-of-graph node representation learning, real-world challenges such as fixed in-graph node embedding and data diversity essentially limit the performance of these methods.

Cross-Cultural Validation of Knowledge About Atrial Fibrillation and Stroke Prevention Questionnaire: A Cross-Sectional Study Among Chinese Patients With Atrial Fibrillation.

Aim: To cross-culturally adapt the Knowledge about Atrial Fibrillation and Stroke Prevention Questionnaire (KAFSP-Q) for Chinese AF patients and validate its effectiveness.

Design: Instrument adaptation and cross-sectional validation.

Methods: The KAFSP-Q was translated into Chinese by using the forward and back translation method.

Moderating effects of chord progressions on the emotional experience of major and minor chords.

Numerous studies have shown the major chords express positive emotions, while minor chords convey negative emotions. However, several research suggest that the association between major/minor chords and emotional valence may vary due to certain musical contextual factors. This study investigates whether the emotional experience associated with major and minor chords is influenced by chord progressions.