Endocannabinoid basis of personality-Insights from animal model of social behavior.

The endocannabinoid system is known to be involved in learning, memory, emotional processing and regulation of personality patterns. Here we assessed the endocannabinoid profile in the brains of mice with strong characteristics of social dominance and submissiveness. A lipidomics approach was employed to assess the endocannabinoidome in the brains of Dominant (Dom) and Submissive (Sub) mice.

Antidepressant-like effects of a chlorogenic acid- and cynarine-enriched fraction from Dittrichia viscosa root extract.

Dittrichia viscosa is a perennial Mediterranean plant used in traditional medicine for "calming purposes", pointing at a possible antidepressant activity of the plant. We conducted chromatographic and bioassay-guided fractionation of D. viscosa root extract to isolate a specific fraction (fraction "K") with antidepressant-like characteristics in vivo and strong antioxidant properties in vitro.

[Efficacy of amizon in the treatment of chronic toxic hepatitis and its immunocorrective action].

Efficacy has been ascertained of a new home-made drug preparation amyzon in the treatment of patients with chronic toxic hepatitis. Shown in the study made was a positive effect on amyzon on biochemical and immunological indices. The administration of amyzon makes for achievement of a long-term clinical and biochemical remission of chronic hepatitis.

[The effect of polysaccharides on thermal denaturation of sarcoplasmic proteins from muscle homogenates].

When meat sarcoplasmic proteins interact with polysaccharides thermodynamic parameters of the systems are changed. The insoluble forms (natural plant matrix from wheat bran, cellulose) provide for partial denaturation of proteins at low temperatures (30-45 degrees C) and intensify subsequent coagulation processes. An increase of enthalpy with their increased concentration was found.

[The effect of dietary fiber on proteolysis].

In the presence of food fibers, proteolysis occurs with the formation of sorption complexes. At the initial stages of hydrolysis, the adsorption of both casein and pepsin is observed, the adsorption influencing the initial rate of hydrolysis. The composition of the sorption layer changes during hydrolysis in favor of intermediates.