[Pathophysiologic characteristics of the reactive toxic stage of acute suppurative peritonitis and ways to enhance the effectiveness of intensive therapy].

The oxygen regimen, circulation, and metabolism were studied in 95 patients in the reactive-toxic stage of diffuse purulent peritonitis. The results of cluster analysis made it possible to determine the clinical and pathophysiological features of the phases of the disease. The phase of compensation was characterized by disorders of mass exchange of plasma water which led to increased index of transcapillary exchange and increased excess of lactate.

[Early signs of decompression of the body in acute suppurative peritonitis and ways of increasing the effectiveness of intensive therapy].

In studying the oxygen regimen, circulation and metabolism in 95 patients with acute purulent peritonitis at the toxic stage, it was established that the disorders in transcapillary exchange and oxygen regimen were the early functional criteria for decompensation of the general state of an organism. Differential, in accordance with a phase of the course of the disease, inclusion into the complex of intensive therapy, beginning from the preoperative preparation and anesthesiologic aid, of ornid and ornid with alupent permitted to improve considerably the results of surgical treatment of the patients.