[The energetic metabolism in newborns in normal conditions and under development of disorders of adaptation in early postnatal period].

The article deals with the prospective complex approach to laboratory analysis of energetic metabolism under states of newborns. The approach provides simultaneous detection of content of main energy substrates, activity of adenosinetriphosphatases and succinate dehydrogenases in umbilical blood, characterized by high sensitivity to hypoxia.

[Condition of erythron in newbord rats with disturbed sensorimotor reflexes].

Early adaptation issues of newborn rats of Wistar population and August line were examined. Absence of the connection between the condition of a female during the pregnancy and the birth, and newborn rats in early postnatal period was revealed.

[The activity of platelet monoamine oxidase, red blood cell Mg-ATPase, and the level of serum magnesium in the acute period of adaptation in neonatal infants].

For early diagnosis of neonatal transient conditions that may become abnormal, it is promising to apply an integrative approach comprising the concurrent definition of the indices characterized by a high sensitivity to hypoxia. This study has investigated the predictive value of platelet monoamine oxidase and red blood cell Mg-ATPase in neonatal infants.

[Effect of early postnatal hypoxia on Wistar and August rats].

It was proved that hypoxia tolerance often goes together with forming of oxidative stress tolerance and has genetic predetermination on hypoxic influence. Interline difference ofhypoxia sensitivity is mainly defined by difference of oxygen-transport systems state. Genetically predetermined differences between investigated lines give the August rats the ability to use mechanisms of resistant strategy more effectively, and the Wistar rats--to use tolerant strategy more effectively.

[Xanthine oxidase as an indicator of neonatal adaptation].

The reactions reflecting adaptation may assume pathological traits under certain conditions. It is necessary to have reliable predictors that characterize adaptive processes. As this criterion, it is expedient to use the most important marker of free radical oxidation, such as xanthine oxidase (XO) activity.