[Isolation of bacterial endotoxins from Pseudomonas putida 36 and Escherichia coli (vulgaris)].

Extracts of endotoxins from Gram-negative bacteria Pseudomonas putida 36 and Escherichia coli (vulgaris) grown upon solid-phase or submerged cultivations were studied. The composition of the extracts was analyzed by gel-filtration. Ps.

[Biotechnological grounds for the regulation of the component composition of cephalosporins in cultures of Acremonium chrysogenum].

The dynamics of cephalosporine C and desacetylcephalosporine C alterations in cultures of Acremonium chrysogenum 309A under different conditions was studied. It was shown expedient to determine the fermantation period by the data of HPLC. Genetic predisposition of the strain used to production of both cephalosporine C and desacetylcephalosporine C is discussed.

[Separation of novobiocin, isnovobiocin and descarbamyl novobiocin by a thin-layer chromatographic method].

A thin-layer chromatographic method for separation of novobiocin, isonovobiocin and descarbamylnovobiocin using Silufol plates was developed. The method is simple and rapid. It provided clear separation of the components and using of diethyl ether, a simple individual separating solvent.