[Rationale of the method of complex treatment for localized breast cancer with the use of methodology of intraoperative radiation therapy after neoadjuvant systemic drug therapy and sentinel lymph node biopsy].

Surgery remains the primary step in the localized forms of breast cancer. To date a growing number of women in the world could be provided with organ-preserving operations (OPO). At large tumor size in relation to the volume of the breast mastectomy is needed.