Oral microbiome diversity and diet quality in relation to mortality.

Aim: To examine the independent and joint associations of oral microbiome diversity and diet quality with risks of all-cause and cause-specific mortality.

Materials And Methods: We included 7,055 eligible adults from the U.S.

No Black Holes from Light.

We show that it is not possible to concentrate enough light to precipitate the formation of an event horizon. We argue that the dissipative quantum effects coming from the self-interaction of light (such as vacuum polarization) are enough to prevent any meaningful buildup of energy that could create a black hole in any realistic scenario.

Effects of the mineralocorticoid receptor antagonist eplerenone in experimental autoimmune encephalomyelitis.

There is growing evidence indicating that mineralocorticoid receptor (MR) expression influences a wide variety of functions in metabolic and immune response. The present study explored if antagonism of the MR reduces neuroinflammation in the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE). Eplerenone (EPLE) (100 mg/kg dissolved in 30% 2-hydroxypropyl-β-cyclodextrin) was administered intraperitoneally (i.

Exposure to endogenous and exogenous sex hormones and reproductive history influence prognosis in women with ALS.

Introduction/aims: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a higher incidence in men suggesting an influence of sex steroids. Our objective was to investigate past exposure to endogenous and synthetic steroids in female ALS patients and controls.

Methods: We administered a questionnaire to 158 postmenopausal women (75 ALS patients and 83 controls).

Semiclassical relativistic stars.

We present strong evidence that semiclassical gravity can give place to self-consistent ultracompact stars beyond the Buchdahl limit. We integrate the semiclassical equations of (spherically symmetric) stellar equilibrium for a constant-density classical fluid. The semiclassical contribution is modelled by a quantum massless scalar field in the only static vacuum state compatible with asymptotic flatness (Boulware vacuum).