Publications by authors named "L I Dvoretski"

The study objective to investigate hematological parameters and determine the relationships between these indicators and body composition in centenarians with coronary artery disease. This work is a cross-sectional study, which enrolled 239 patients over 90 years old hospitalized with a diagnosis of coronary artery disease; most of them (67,8%) were women. The age of the patients ranged from 90 to 106 years, averaging 92,8 (±2,5) years.

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The study objective was to compare the CKD-EPI, MDRD, BIS1, and Cockroft-Gault equations for calculating GFR, and analyze the various relationships between the glomerular filtration rate and clinical and laboratory parameters in long-living patients with coronary artery disease (CAD). A cross-sectional study of 270 patients from 90 to 106 years old, hospitalized with CAD diagnosis, was performed. The mean estimated GFR according to CKD-EPI was 51,4±14,2 ml/min, MDRD - 50,9±13,4, BIS1 - 38,4±7,7, Cockroft-Gault - 40,6±12,6 ml/min.

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The results of a study of the concentration of TNF-α as well as the relationship of this cytokine with a number of pathological conditions in very elderly patients with coronary artery disease compared with the control group of patients without CAD are presented in the article. The average group concentration of TNF-α reached 9,2+4,7 pg/ml (from 3,9 to 31,9 pg/ml) with normal TNF-α values of less than 8,1 pg/ml. An increase in the level of TNF-α was detected in 54,6% of patients.

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The results of cross-sectional study aimed to investigate bone mineral density (BMD) in 202 patients over 90 years old with coronary artery disease are presented in this atricle. Normal BMD indices in the lumbar spine were observed in 40,9%, osteoporosis - in 26,9%, osteopenia - in 32,2% of patients. Normal BMD indices in the proximal femur were observed in 21,3%, osteoporosis - in 39,9%, and osteopenia - in 38,8% of patients.

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The review covers issues of epidemiology, diagnostics, management strategy, and treatment outcomes in patients with non-ST elevation acute coronary syndrome. Numerous factors affecting the choice of an invasive strategy are analyzed as well as its correspondence to existing recommendations of patient's management. The stratification of risk of development of adverse coronary events, which is a part of the formation of a treatment strategy, is discussed.

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