Influence of occupational vibration on development of resistance to insuline and of II type diabetes mellitus.

The authors revealed influence of occupational vibration on development of resistance to insulin and of II type diabetes mellitus in miners. With that, increased serum insulin level was diagnosed in the workers. Occurrence of patients with.

[Criterial value of oxidative stress parameters in exposure to vibration].

The article covers results of study concerning metabolic processes in workers exposed to vibration. Findings are lipid peroxidation processes activation, depressed anti-oxidant system, changes in intracellular exchange processes, dependence of the studied parameters change on length of service with vibration exposure.

[Responsiveness of peripheral blood neutrophils under exposure to industrial aerosols].

There was made an evaluation of the functional state of peripheral blood neutrophils in 230 workers with dustbreathing risks (mine, metallurgical and machine-building works). There was noted the change in the responsiveness of neutrophils in dependence on both composition and the intensity of the exposure of industrial aerosols to the human body. There was followed the relation between the pathology of the respiratory system with the biochemical changes of granulocytes.

[The informative laboratory biomarkers for detection of negative impact of vibration on organism of workers].

The analysis was carried out concerning new characteristics of diagnostic informativeness of particular biochemical, immunologic, cytochemical and hematologic indicators under impact of vibration on human organism. It is established that high diagnostic informativeness is typical for indicators of oxidation metabolism (alpha-superoxide dismutase, myeloperoxidase in neutrophils, alpha-tokopherol), humoral immunity (IgA, IgG), hematologic indicators (corpuscular volume, peroxide hemolysis of erythrocytes, thrombocytes aggregation velocity) and level of creatinine in urine reflecting damages of muscular tissue. The levels of biomarkers mentioned above begin to alter in healthy workers and in individuals under suspicion of vibration disease.

[Influence of vibration on changes in S100B protein content of peripheral blood in miners].

The authors studied influence of vibration on serum neurotropic protein S100B level in miners. Vibration appeared to cause significant effect on increase of this protein level. With that, there is a moderate correlation between the protein level and intensity of the vibration effect.