Publications by authors named "L Hornung"
We performed a needs assessment to determine the essential elements for a curriculum teaching burn care during Large Scale Combat Operations against peer/near-peer adversaries within multi-domain contested combat environments. Virtual and face-to-face site visit meetings were conducted with 20 stakeholders at 3 levels: 1) Subject Matter Experts (SMEs) in military burn casualty care at the U.S.
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- Vaccination before solid organ transplantation (SOT) is essential because immunosuppression post-transplant affects vaccine responses, but not much is known about how effective these vaccines are afterward.
- In a study of 136 SOT recipients, only 27.9% showed protection against hepatitis B virus (HBV) and 42.6% against invasive pneumococcal disease (IPD) after transplantation despite being vaccinated before the procedure.
- Patients who had seroprotection when listed for transplantation were significantly less likely to have a non-response to both HBV and IPD, indicating that early vaccination is crucial for improving post-transplant outcomes.
Pituitary deficiencies related to optic nerve hypoplasia and visual acuity.
Clin Endocrinol (Oxf)
November 2024
Objective: Optic nerve hypoplasia (ONH), the congenital underdevelopment of the optic nerve, is an increasing cause of visual impairment and is associated with pituitary dysfunction. Past studies have focused on the relationship between ONH, pituitary deficiencies, and brain imaging. However, recent studies have demonstrated the true risk for hypopituitarism lies with the presence or absence of ONH, irrespective of midline brain findings.
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- * Out of 181 patients, most had mild AP, while a smaller percentage faced moderate or severe cases; results indicated stable BMI over 12 months, but significant deficiencies in Vitamin D, ferritin, and other nutrients were observed.
- * Notably, 13% of patients developed pre-diabetes or diabetes after the episode, and 24% experienced low albumin levels shortly after, indicating potential concerns for long-term nutritional health in this population.