Publications by authors named "L Holbrook"
Reintegration Following Amputation: A Biopsychosocial Approach.
Phys Med Rehabil Clin N Am
November 2024
Article Synopsis
- Reintegration after limb loss depends on the interplay of mental health, environmental factors, and physical aspects like pain and prosthetic use.
- While some individuals successfully adapt and experience personal growth, others face significant challenges during this transition.
- Interdisciplinary teams play a crucial role by identifying and addressing barriers early on, helping amputees return to normal activities like driving more swiftly, which enhances overall quality of life.
Article Synopsis
- This study evaluates the long-term clinical outcomes of non-modular dual-mobility acetabular components in patients at least 2 years post-total hip arthroplasty (THA), focusing on factors like patient satisfaction, pain, and function.* -
- The research involved 316 patients across three sites, revealing high scores in hip function and patient satisfaction, with minimal complications and low rates of revisions or dislocations.* -
- Results indicate that non-modular dual-mobility devices offer good survivorship and low adverse event rates, suggesting they are a reliable option for improving patient outcomes after THA.*
Nox1 signaling is a causal key element in arterial hypertension. Recently, we identified protein disulfide isomerase A1 (PDI) as a novel regulatory protein that regulates Nox1 signaling in VSMCs. Spontaneously hypertensive rats (SHR) have increased levels of PDI in mesenteric resistance arteries compared with Wistar controls; however, its consequences remain unclear.
View Article and Find Full Text PDFTotal and regional deposition of inhaled electronic cigarette (E-cig) particles in the respiratory tract (RT) depends on both physical properties of the inhaled particles and biological factors of users, for example, breathing pattern or puff profile, airway anatomy, and regional ventilation. Accurate particle sizing of E-cig aerosols is essential for predicting particle deposition in the RT. Studies using a variety of sizing methods have shown mass median aerodynamic diameters ranging from 0.
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