EXPRESS: Deliberate Search for Analogous Cases Aids the Retrieval and Transfer of Suboptimally-Encoded Memory Items.

Even though spontaneous retrieval of analogous cases lacking surface similarity with a target situation typically requires achieving an abstract representation of the target situation, recent studies on analogical argumentation suggest that the deliberate disposition to search for analogous cases in long-term memory (LTM) suffices to increase cross-domain retrieval significantly. However, a limitation of these studies concerns the impossibility to determine whether the analogous situations reported were invented rather than retrieved, and whether there were instances of analogical retrieval that were not reflected in participants' arguments. To overcome these shortcomings, Experiment 1 resorted to a traditional transfer paradigm where a base analog is learned prior to the presentation of the target situation during a contextually-separated phase.

Multispecies emergence of dual carbapenemase-producing Enterobacterales recovered from invasive infections in Chile.

Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) represent a significant global threat. The emergence of dual CP-CRE is particularly alarming, as they can potentially compromise the efficacy of newer antibiotics, further decreasing therapeutic alternatives. Herein, we report the emergence of multiple species of CP-CRE recovered from invasive infections in Chile that simultaneously harbor and and provide an in-depth genomic characterization of these worrisome pathogens.

Lateral flow immunoassay for simultaneous detection of C. difficile, MRSA, and K. pneumoniae.

Mainly performed within a rapid diagnostic tests company, a lateral flow (LF) system using gold nanoparticles (AuNPs) as transducers is presented able to detect three bacteria of interest, of relevance for antimicrobial resistance (AMR): Clostridioides difficile, methicillin-resistant Staphylococcus aureus (MRSA), and Klebsiella pneumoniae, with a limit of detection of 25 ng/mL of glutamate dehydrogenase (GDH) for C. difficile, 36 ng/mL of penicillin-binding protein 2a (PBP2a) for MRSA, and 4 × 10 CFU/mL for K. pneumoniae.