Analysis of factors influencing the choice for a centre for obstetrical and gynaecological patients.

Purpose: The purpose of this study was to analyse the factors that influence patients` choice of obstetric and gynaecological medical centre.

Methods: Patients attending the gynaecological and obstetric outpatient department (gyn./obs.

Large language models (LLMs) and the institutionalization of misinformation.

Large language models (LLMs), such as ChatGPT, flood the Internet with true and false information, crafted and delivered with techniques that psychological science suggests will encourage people to think that information is true. What's more, as people feed this misinformation back into the Internet, emerging LLMs will adopt it and feed it back in other models. Such a scenario means we could lose access to information that helps us tell what is real from unreal - to do 'reality monitoring.

Tacrolimus-why pharmacokinetics matter in the clinic.

The calcineurin inhibitor (CNI) Tacrolimus (Tac) is the most prescribed immunosuppressant drug after solid organ transplantation. After renal transplantation (RTx) approximately 95% of recipients are discharged with a Tac-based immunosuppressive regime. Despite the high immunosuppressive efficacy, its adverse effects, narrow therapeutic window and high intra- and interpatient variability (IPV) in pharmacokinetics require therapeutic drug monitoring (TDM), which makes treatment with Tac a major challenge for physicians.

Development of the Saini-Hodgins Addiction Risk Potential of Games (SHARP-G) Scale: An International Delphi study.

Background And Objectives: As the gaming industry experiences exponential growth, concerns about gaming disorder (GD) also grow. It is crucial to understand the structural features of games that can interact with individual characteristics of gamers to promote GD. This research consolidates the views of an international body of panelists to create an assessment tool for gauging the addictive potential of distinct games.

Urinary Dickkopf 3 Is Not an Independent Risk Factor in a Cohort of Kidney Transplant Recipients and Living Donors.

Urinary dickkopf 3 (uDKK3) is a marker released by kidney tubular epithelial cells that is associated with the progression of chronic kidney disease (CKD) and may cause interstitial fibrosis and tubular atrophy. Recent evidence suggests that uDKK3 can also predict the loss of kidney function in CKD patients and kidney transplant recipients, regardless of their current renal function. We conducted a prospective study on 181 kidney transplant (KTx) recipients who underwent allograft biopsy to determine the cause, analyzing the relationship between uDKK3 levels in urine, histological findings, and future allograft function progression.