Comprehensive bioinformatics analysis of prognosis and immunotherapy in lung adenocarcinoma.

Background: Research has shown that genetic mutations play an important role in the prognosis of lung adenocarcinoma (LUAD). However, the genes that influence the prognosis and immunotherapy of lung cancer patients have not yet been thoroughly studied. In this study, data from The Cancer Genome Atlas (TCGA) Program and other databases were used to identify the survival-related genes in LUAD.

Sex differences in the association between metabolic disorder and inflammatory cytokines in Han Chinese patients with chronic schizophrenia.

Background: Previous evidence suggests that immune-inflammatory dysfunction plays an important role in metabolic disorder (MD) of patients with schizophrenia, yet studies on sex differences in the association between both are limited. The current study aimed to investigate sex differences in the association between MD and inflammatory cytokines in Han Chinese patients with chronic schizophrenia (CS).

Methods: This multicentre cross-sectional study was conducted in one general hospital and two psychiatric hospitals in Anhui Province, China.

The reliability and quality of short videos as health information of guidance for lymphedema: a cross-sectional study.

Background: The prevalence of lymphedema is rising, necessitating accurate diagnostic and treatment information for affected patients. Short video-sharing platforms facilitate access to such information but require validation regarding the reliability and quality of the content presented. This study aimed to assess the reliability and quality of lymphedema-related information on Chinese short video-sharing platforms.

Autophagy serves as a protective effect against inflammatory injury of oxidative stress in ARPE-19 cell.

Aim: To test the effect of autophagy on inflammatory damage resulting from oxidative stress in adult retinal pigment epithelial cell line (ARPE-19).

Methods: ARPE-19 cells were pretreated with 200 and 600 µmol/L hydrogen peroxide (HO) at various time intervals. The changes of cell morphology, cell viability, reactive oxygen species (ROS) level, autophagic activity, and the inflammatory cytokines (TNFα, IL-6, and TGFβ) were measured at baseline and after treatment with autophagy inducer rapamycin (Rapa) and suppressor wortmannin (Wort) or shATG5.

Is simpler better? Semantic content modulates the emotional prosody perception in Mandarin-speaking children with autism spectrum disorder.

Introduction: It is still under debate whether and how semantic content will modulate the emotional prosody perception in children with autism spectrum disorder (ASD). The current study aimed to investigate the issue using two experiments by systematically manipulating semantic information in Chinese disyllabic words.

Method: The present study explored the potential modulation of semantic content complexity on emotional prosody perception in Mandarin-speaking children with ASD.