Publications by authors named "L H W Lum"
Purpose: Radiation Therapy (RT) can modulate the immune system and generate anti-tumor T cells. However, this anti-tumor-activity is countered by radiation-induced immunosuppression (RIIS). Clinical advantages of proactively sparing RT dose to immune rich organs have not previously been evaluated.
View Article and Find Full Text PDFBackground: Low-income pregnant patients are at high risk of postpartum depression (PPD). Mothers and Babies (MB) is a cognitive behavioral therapy-based program that prevents up to 50% of de novo PPD when provided in person to low-income Spanish- and English-speaking people who are pregnant without depression. MB is limited by the need for trained personnel to support it.
View Article and Find Full Text PDFPrecision gene editing enables massively parallel identification of cancer-promoting genes.
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- Postpartum depression (PPD) is more prevalent in pregnant individuals facing social challenges, and the Mothers and Babies (MB) program effectively lowers PPD rates but requires trained personnel to implement.
- The goal of the study is to develop MBapp, a smartphone application based on the MB program, using qualitative feedback from target users to enhance its functionality.
- The app's design includes features like personalized notifications, multimedia content, and gamification, and user feedback led to significant modifications, which were recorded using a systematic framework for reporting changes to evidence-based interventions.
Identifying biomarkers in non-small cell lung cancer (NSCLC) can improve diagnosis and patient stratification. We evaluated plasmas and sera for interleukins (IL)-11, IL-6, IL-8, IL-17A, and IL-33 as biomarkers in primary NSCLC patients undergoing surgical treatment against normal volunteers. Exhaled-breath condensates (EBCs), a potential source without invasive procedures, were explored in normal individuals.
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