Publications by authors named "L H Thomassen"
Article Synopsis
- The study investigates the use of modified MRI mismatch criteria for administering intravenous thrombolysis (IVT) to wake-up stroke (WUPS) patients, focusing on those with partial mismatch.
- Conducted at Stavanger University Hospital, it included 78 WUPS patients, assessing their clinical outcomes based on NIHSS and mRS scores after 3 months, alongside safety concerns like intracranial hemorrhage (ICH).
- The findings revealed that patients with the best outcomes had a DWI/FLAIR mismatch and no instances of ICH were reported, supporting the modified criteria's effectiveness for selecting WUPS patients for IVT.
Objectives: Cerebral microemboli can be detected by transcranial Doppler monitoring (TCDM) and may elucidate stroke etiology, the effect of preventive therapy, and the risk of stroke recurrence. Microemboli detection is usually performed for up to 60 minutes, but due to temporal variability, microembolization may be missed if the monitoring time is too short. We aimed to assess the time course of microembolization in acute ischemic stroke and explore the utility of prolonged and repeated microemboli detection.
View Article and Find Full Text PDFBackground: Several studies have shown that stroke mimics occur more often among young patients. Our aims were to identify the common mimics in young patients under the age of 60 years who received thrombolysis, to analyze the risk of hemorrhage after treatment with thrombolysis, and to identify risk factors and clinical parameters that might identify mimics in this group.
Methods: Norwegian Tenecteplase Stroke Trial was a phase-3 trial investigating safety and efficacy of tenecteplase vs.
Background The optimal dose of tenecteplase in acute ischemic stroke remains to be defined. We present a pooled analysis of the 2 NOR-TESTs (Norwegian Tenecteplase Stroke Trials) exploring the efficacy and safety of tenecteplase, 0.4 mg/kg.
View Article and Find Full Text PDFComparison of diffusion weighted imaging b0 with T2*-weighted gradient echo or susceptibility weighted imaging for intracranial hemorrhage detection after reperfusion therapy for ischemic stroke.
Neuroradiology
November 2023
Purpose: Diffusion-weighted imaging (DWI) b0 may be able to substitute T2*-weighted gradient echo (GRE) or susceptibility-weighted imaging (SWI) in case of comparable detection of intracranial hemorrhage (ICH), thereby reducing MRI examination time. We evaluated the diagnostic accuracy of DWI b0 compared to T2*GRE or SWI for detection of ICH after reperfusion therapy for ischemic stroke.
Methods: We pooled 300 follow-up MRI scans acquired within 1 week after reperfusion therapy.