Publications by authors named "L H Scudeler"
Background: Longitudinal data on reverse cardiac remodeling and outcomes after transcatheter edge-to-edge repair (TEER) are limited.
Methods: A total of 78 patients with severe mitral regurgitation (MR) were included retrospectively. All patients had echocardiography at baseline and again six months after TEER.
Article Synopsis
- The study investigates the prevalence and impact of prosthesis-patient mismatch (PPM) in patients undergoing transcatheter aortic valve replacement (TAVR) on heart damage and mortality.
- A cohort of 963 patients was analyzed, revealing that 18% experienced PPM post-TAVR, with 7.7% having severe cases.
- Those with PPM exhibited significant heart changes after one year, including increased left ventricle size and more paravalvular aortic regurgitation compared to those without PPM.
Ultrathin-strut drug-eluting stents (DES) have been related to potential improvement in stent-related outcomes compared with thicker-struts DES. However, comparisons among different ultrathin devices are lacking. All randomized controlled trials comparing ultrathin (struts thickness <70 µm) and thicker-struts DESs in an all-comers population were included.
View Article and Find Full Text PDFBackground: The clinical value of high-risk coronary plaque characteristics (CPCs) to inform intensified medical therapy or revascularization of non-flow-limiting lesions remains uncertain.
Objectives: The authors performed a systematic review and meta-analysis to study the prognostic impact of CPCs on patient-level and lesion-level major cardiovascular adverse events (MACE).
Methods: Thirty studies (21 retrospective, 9 prospective) with 30,369 patients evaluating the association of CPCs with MACE were included.
Article Synopsis
- The study investigates the prevalence of transthyretin cardiac amyloidosis (ATTR-CA) in patients undergoing transcatheter aortic valve replacement (TAVR) due to severe aortic stenosis (AS), noting that detection is often challenging among this group.
- Out of 107 patients evaluated, 6 were confirmed to have ATTR-CA, resulting in a prevalence rate of 7.1%, with ATTR-CA patients being older and exhibiting more severe heart and kidney damage compared to those without the condition.
- The research highlights unique ECG features, such as bifascicular block, that are significantly associated with dual pathology (both AS and ATTR-CA), indicating the need for improved detection methods in these patients.