Elevation of ANXA1 associated with potential protective mechanism against ferroptosis and immune cell infiltration in age-related macular degeneration.

Background: Age-related macular degeneration (AMD), is a neurodegenerative ocular disease. This study investigated the role of ferroptosis-related genes and their interaction with immune cell infiltration in AMD.

Methods: We screened differential expression genes (DEGs) of AMD from data sets in Gene Expression Omnibus.

CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis.

Triple-negative breast cancer (TNBC) is an aggressive molecular subtype of breast cancer characterized by a high recurrence rate, poor prognosis, and elevated mortality. Identifying novel molecular targets is crucial for developing more effective therapeutic strategies against TNBC. Recent studies have highlighted the role of circular RNAs (circRNAs) in the progression of TNBC.

Preparation of bioactive film for regulating chlorine dioxide release based on the hygroscopic properties of chitosan and its application in broccoli preservation.

An active packaging film was developed by integrating sodium chlorite (SC) and citric acid (CA) into a Poly(lactic acid)/Poly(butylene adipate-co-terephthalate) (PLA/PBAT) matrix, enabling the controlled release of chlorine dioxide (ClO) gas. The release of ClO was further regulated by introducing chitosan (CS) into the film, leveraging its hygroscopic properties. The results showed that when the addition amount of CS was 4 wt%, the water vapor transmission rate increased by 41.