Publications by authors named "L H John"
The greater sciatic, lesser sciatic and obturator foramina are openings in the pelvis through which pelvic lesions can herniate, leading to the formation of rare dumbbell tumours. We present the case of a man in his late 60s, who presented with obstructed defecation. A per rectal examination revealed a palpable right sided rectal mass.
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- - The study investigates how changes in spleen signal on various MRI sequences relate to the amount of plasma cell infiltration in the bone marrow of multiple myeloma patients, aiming to find a possible indicator for disease severity.
- - Researchers analyzed 45 newly diagnosed MM patients using whole-body MRI and found that spleen signal intensity negatively correlated with bone marrow plasma cell infiltration, meaning higher infiltration resulted in lower spleen signal.
- - Results suggest a significant association between spleen signal intensity, particularly on T2-weighted images, and tumor burden, providing potential insights for assessing disease in multiple myeloma patients.
Background: Drugs used to treat rheumatic disease are associated with pneumotoxicity (drug-induced lung disease), but little is known about associated risk factors.
Aim: To determine expert physician-perceived risk factors for developing pneumotoxicity in patients with rheumatologic conditions.
Methods: A modified international 3-tier Delphi exercise was performed.
Highly pathogenic Burkholderia pseudomallei is the causative agent of melioidosis, a neglected tropical disease endemic in Southeast Asian tropical region. This bacterium encompasses diverse virulence factors which further undergo dynamic gene-expression flux as it transits through distinct environmental niches within the host which may lead to manifestation of differential clinical symptoms. B.
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