Publications by authors named "L H Gerber"

Modifiable risk factors associated with cognitive functioning are important for identifying potential targets for intervention development. Although there are a few recognized modifiable risk factors (e.g.

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Backgrounds: People with metabolic dysfunction-associated steatotic liver disease (MASLD) frequently report fatigue. This symptom is associated with hepatic inflammation and fibrosis. FibroScan-aspartate aminotransferase (FAST) score is a noninvasive measurement tool that can be used to assess the severity of MASLD.

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Article Synopsis
  • The study focuses on the crucian carp, a fish that survives in low-oxygen conditions and manages oxidative stress during re-oxygenation, making it a valuable model for understanding mitochondrial resilience.
  • High-resolution respirometry was used to compare mitochondrial function and reactive oxygen species (ROS) production between crucian carp and mice at different temperatures (37°C and 8°C).
  • Findings revealed significant differences in HO (hydrogen peroxide) production between species, suggesting that mitochondrial adaptations related to thermal sensitivity and complex efficiency could inform future advancements in transplant medicine.
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Demographic processes can substantially affect a species' response to changing ecological conditions, necessitating the combined consideration of genetic responses to environmental variables and neutral genetic variation. Using a seascape genomics approach combined with population demographic modelling, we explored the interplay of demographic and environmental factors that shaped the current population structure in Indo-Pacific bottlenose dolphins (Tursiops aduncus) along the Western Australian coastline. We combined large-scale environmental data gathered via remote sensing with RADseq genomic data from 133 individuals at 19 sampling sites.

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Article Synopsis
  • * It finds that higher MASLD prevalence correlates with rising obesity, type 2 diabetes rates, and low physical activity, with notable variances based on a country’s socio-demographic index (SDI).
  • * The results suggest that public health strategies must be tailored to address the unique socio-economic conditions in different regions to effectively tackle MASLD and its related health risks.
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