VPO1 Promotes Programmed Necrosis of Cardiomyocytes in Rats with Chronic Heart Failure by Upregulating CYLD.

Background: Chronic heart failure (CHF) is a serious cardiovascular condition. Vascular peroxidase 1 (VPO1) is associated with various cardiovascular diseases, yet its role in CHF remains unclear. This research aims to explore the involvement of VPO1 in CHF.

Analysis of genetic instability induced by radon exposure in iron mine processing workers in Shandong Province, Northern China.

Background: Radon, a colorless and odorless radioactive gas, poses serious health risks. It is the second leading cause of lung cancer and notably increases lung cancer risk in smokers. Although previous epidemiological studies have mainly examined lung cancer rates in miners, the effects of radon on genomic stability and its molecular mechanisms are not well understood.

An approach for preparing multifunctional cellulose fabrics with hydrophilic-hydrophobic flexible modulation, salt-free dyeing and antibacterial performance.

A straightforward and effective approach was introduced for creating a multifunctional cellulose fabric in this paper. The epoxy groups in epoxidized soybean oil participated in ring-opening reactions with hydroxyl groups present in cellulose fibers and amino groups found in polyhexamethylene guanidine hydrochloride, respectively, under alkaline conditions. Polyhexamethylene guanidine hydrochloride could introduce cationic groups, while epoxidized soybean oil could contribute hydrophobic alkane chains.

Study on numerical simulation of groundwater flow field and slope stability in multi-aquifer open pit mine.

Water is one of the most important influences on slope stability in open pit mines. In order to solve the problem of slope stability analysis in multi-aquifer open pit mines, the open pit mine in Block I of Thar Coalfield in Pakistan with multiple aquifers was taken as the research background. The groundwater flow field at different excavation phases was analyzed by numerical simulation method.

The Effect of Meloxicam on Inflammatory Response and Oxidative Stress Induced by in Bovine Mammary Epithelial Cells.

() is a significant pathogen associated with clinical mastitis in cattle. Anti-inflammatory drugs are necessary to alleviate pain and inflammation during clinical mastitis. Among many drugs, meloxicam (MEL) has been widely used in clinical mastitis because of its excellent inhibitory effect on the cyclooxygenase-2 (COX-2) enzyme.