Publications by authors named "L H Engrav"
Article Synopsis
- * In a randomized controlled trial, one group received standard outpatient care while the other group, aided by an ECC, received additional support through scheduled phone calls and coordination of services related to rehabilitation.
- * Ultimately, the study found no significant differences in patient outcomes between the two groups after 6 and 12 months, although all participants valued the personalized goal-setting process provided by the ECC.
Purpose: To estimate quality-of-life loss per serious burn survivor in a large U.S. cohort.
View Article and Find Full Text PDFPruritus (itching) is a common and distressing complaint after injury. The purpose of this study was to investigate self-reported postburn pruritus in a large, multisite cohort study of adult burn survivors. Descriptive statistics, general linear regression, and mixed model repeated measures analyses were employed to test statistical significance.
View Article and Find Full Text PDFBackground: Burn demographics, prevention and care have changed considerably since the 1970s. The objectives were to 1) identify new and confirm previously described changes, 2) make comparisons to the American Burn Association National Burn Repository, 3) determine when the administration of fluids in excess of the Baxter formula began and to identify potential causes, and 4) model mortality over time, during a 36-year period (1974-2009) at the Harborview Burn Center in Seattle, WA, USA.
Methods And Findings: 14,266 consecutive admissions were analyzed in five-year periods and many parameters compared to the National Burn Repository.
Background: Hypertrophic scar was first described over 100 years ago; PubMed has more than 1,000 references on the topic. Nevertheless prevention and treatment remains poor, because 1) there has been no validated animal model; 2) human scar tissue, which is impossible to obtain in a controlled manner, has been the only source for study; 3) tissues typically have been homogenized, mixing cell populations; and 4) gene-by-gene studies are incomplete.
Methodology/principal Findings: We have assembled a system that overcomes these barriers and permits the study of genome-wide gene expression in microanatomical locations, in shallow and deep partial-thickness wounds, and pigmented and non-pigmented skin, using the Duroc(pigmented fibroproliferative)/Yorkshire(non-pigmented non-fibroproliferative) porcine model.