Publications by authors named "L Gutierrez-Rojas"

Background: Mental disorders significantly impact individuals and societies globally. Addressing societal stigma is crucial, as it affects help-seeking behaviors and the effectiveness of treatment for mental disorders.

Objective: This study aims to explore the knowledge and perceptions of the Spanish population toward mental disorders and their treatment, assess changes in mental health stigma over time, and examine variations across sociodemographic variables by comparing current results with previous studies.

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Background: Treatment-resistant depression (TRD) is defined as the failure of at least two antidepressants in adequate doses and timing during a major depressive episode. Esketamine intranasal (ESK-IN) has been approved by the Food and Drug Administration and the European Medicines Agency for the treatment of TRD in combination with other antidepressants.

Aims: To assess the effectiveness and tolerability of a sample of TRD patients who received treatment with ESK-IN as part of the compassionate use program.

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Article Synopsis
  • Mental health issues like anxiety and depression are on the rise globally, and this study looks at how cortisol and sex hormones affect mental health in healthy middle-aged adults.
  • The research involved 73 participants aged 45-65, where various hormone levels were measured alongside self-reported mental health metrics using established surveys.
  • Findings revealed that higher levels of testosterone and other hormones were linked to lower depression scores in men and women, indicating that normal levels of these hormones may promote better mental health.
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